The Structural Biology and Imaging (SBI) Core
Hans Grossniklaus examining slides in The L.F. Montgomery Laboratory, a dynamic patient care, diagnostic, research and education service at Emory Eye Center in Atlanta. Montgomery Lab is a free-standing, independently-licensed laboratory established in 1940.
Hans Grossniklaus, MD, MBA, Director (EEC, EUSOM)
SBI Core Lab Team, Emory Eye Center
Banks, Kiara, Administrative Assistant
Jones, Nyasia, Pre-doctoral Fellow, 4+1 Masters in Cancer Biology and Translational Oncology Student
Kang, Shin Jeong, MD PhD, Post-Doctoral Fellow
L'Hernault, Nancy, MA, Electronic Microscopy Technologist 2
Liu, Pingbo, Histology Technician
Mao, Xiaoqun, PhD, Histology Technician
Story, Jamie, Pre-Doctoral Fellow
Yang, Hua, MD PhD, Post-Doctoral Fellow
Zhang, Qing, MD PhD, Post-Doctoral Fellow
The Structural Biology and Imaging (SBI) Core enhances vision research of AVRC members by assisting them in determining the relationship between normal and abnormal tissue structure in eye diseases, disease models and after experimental treatments.
The core provides facilities and services for AVRC members to determine structural changes and how they relate to function through histology, electron microscopy, confocal scanning laser microscopy and experimental animal surgery imaging. It also supports obtaining structural data and interpretation of this data for new initiatives of AVRC members with an emphasis on retinal function, retinal degeneration/injury, RPE morphometry, ocular oncology, and gene/drug delivery.
Hans E. Grossniklaus MD signing out pathology cases with Svetlana Cherepanoff MD, visiting scholar from Australia and Caroline Craven MD, Emory Eye Center Ocular Oncology/Pathology fellow.
The SBI Core enables localization of proteins involved with control of retinal function in health and disease; imaging of tissue changes in retinal and optic nerve degenerations; correlation of RPE morphometric changes with genotype and function; development of imaging techniques for primary and metastatic ocular tumors, including tissue correlations with MRI contrast agents and tele-imaging; and studying ocular tissue changes relative to gene and drug delivery to the posterior ocular compartment.